Deformable and articulated 3D reconstruction from monocular video sequences

PhDThis thesis addresses the problem of deformable and articulated structure from motion from monocular uncalibrated video sequences. Structure from motion is defined as the problem of recovering information about the 3D structure of scenes imaged by a camera in a video sequence. Our study aims at the challenging problem of non-rigid shapes (e.g. a beating heart or a smiling face). Non-rigid structures appear constantly in our everyday life, think of a bicep curling, a torso twisting or a smiling face. Our research seeks a general method to perform 3D shape recovery purely from data, without having to rely on a pre-computed model or training data. Open problems in the field are the difficulty of the non-linear estimation, the lack of a real-time system, large amounts of missing data in real-world video sequences, measurement noise and strong deformations. Solving these problems would take us far beyond the current state of the art in non-rigid structure from motion. This dissertation presents our contributions in the field of non-rigid structure from motion, detailing a novel algorithm that enforces the exact metric structure of the problem at each step of the minimisation by projecting the motion matrices onto the correct deformable or articulated metric motion manifolds respectively. An important advantage of this new algorithm is its ability to handle missing data which becomes crucial when dealing with real video sequences. We present a generic bilinear estimation framework, which improves convergence and makes use of the manifold constraints. Finally, we demonstrate a sequential, frame-by-frame estimation algorithm, which provides a 3D model and camera parameters for each video frame, while simultaneously building a model of object deformation

Anthropogenic impact on river basins: temporal evolution of sediment classes and accumulation rates in the Northern Tyrrhenian Sea, Italy

Abstract In this study, sedimentological and geochronological data from sections of a core (GRT50) collected in the Northern Latium coastal area were compared to data on pluviometric (rainfall) trends, river flows and the temporal evolution of human interventions in the three most important hydrographic basins (Mignone, Marta and Fiora) of this coastal area. The statistical analysis of pluviometric trends identified variations due to a decreasing trend in the Fiora river basin, whereas in the two other locations the decrease was not so significant. Data from the sedimentological analysis of the core confirmed a progressive decrease in the sandy component, which declined from about 30% to the current level of 7% over the last 36 years. There was no significant variation in the sediment mass accumulation rates (MAR), which were characterized by an almost cyclic trend that was probably determined by the most intense floods in the study area. The results revealed that the variations caused by the fluvial processes have affected the water runoff of the Fiora River, and that the consequent decrease in the sand production has been responsible for the recession of beaches in the coastal area between Tarquinia and Montalto di Castro

Anterior Glenoid Rim Fracture Following Use of Resorbable Devices for Glenohumeral Stabilization

Background Resorbable anchors are widely used in arthroscopic stabilization of the shoulder as a means of soft tissue fixation to bone. Their function is to ensure repair stability until they are replaced by host tissue. Complications include inflammatory soft tissue reactions, cyst formation, screw fragmentation in the joint, osteolytic reactions, and enhanced glenoid rim susceptibility to fracture. Purpose To evaluate resorption of biodegradable screws and determine whether they induce formation of areas with poor bone strength that may lead to glenoid rim fracture even with minor trauma. Study Design Case series; Level of evidence, 4. Methods This study evaluated 12 patients with anterior shoulder instability who had undergone arthroscopic stabilization with the Bankart technique and various resorbable anchors and subsequently experienced redislocation. The maximum interval between arthroscopic stabilization and the new dislocation was 52 months (mean, 22.16 months; range, 12-52 months). The mean patient age was 31.6 years (range, 17-61 years). The persistence or resorption of anchor holes; the number, area, and volume of osteolytic lesions; and glenoid erosion/fracture were assessed using computed tomography scans taken after redislocation occurred. Results Complete screw resorption was never documented. Osteolytic lesions were found at all sites (mean diameter, 5.64 mm; mean depth, 8.09 mm; mean area, 0.342 cm2; mean volume, 0.345 cm3), and all exceeded anchor size. Anterior glenoid rim fracture was seen in 9 patients, even without high-energy traumas (75% of all recurrences). Conclusion Arthroscopic stabilization with resorbable devices is a highly reliable procedure that is, however, not devoid of complications. In all 12 patients, none of the different implanted anchors had degraded completely, even in patients with longer follow-up, and all induced formation of osteolytic areas. Such reaction may lead to anterior glenoid rim fracture according to the literature and as found in 75% of the study patients with local osteolysis (9/12). Reducing anchor number and/or size may reduce the risk of osteolytic areas and anterior glenoid rim fracture

Ion beams delivered by two accelerating gaps for industrial and therapeutic applications

Laser ion sources offer the possibility to get ion beams utilizable to improve particle accelerators. Today many laboratories, as well as the LEAS, are involved to develop accelerators of very contained dimensions, easy to be installed in little laboratories and hospitals. Pulsed lasers at intensities of the order of 108 W/cm2 and of ns pulse duration, interacting with solid matter in vacuum, produce plasma of high temperature and density. The charge state distribution of the plasma generates high electric fields which accelerate ions along the normal to the target surface. The energy of emitted ions has a shifted Maxwell-Boltzmann distribution which depends on the ion charge state. To increase the ion energy, a post-acceleration system can be employed by means of high voltage power supplies of about 100 kV. The post acceleration system results a good method to obtain high ion currents using a not expensive system and the final ion beams find interesting applications in the field of the ion implantations, hadrontherapy, scientific applications and industrial use. In this work we study the electromagnetic and geometric proper-ties, like the emittance of the beams delivered by Cu target. Plasma‟s characterization was performed us-ing a Faraday cup for the electromagnetic characteris-tics, while for the geometric ones by adopting a pep-per pot system. Applying 60 kV of accelerating volt-age and a laser irradiance of 0.1 GW/cm2, we obtain 5.5 mA of output current and a normalized beam emittance of 0.2 π mm mrad. The brightness of the beams was 137 mA(p mm mrad)-2

Iatrogenic Side Effects of Pain Therapies

Pain regimens, particularly for chronic cancer and noncancer pain, must balance the important analgesic benefits against potential risks. Many effective and frequently used pain control regimens are associated with iatrogenic adverse events. Interventional procedures can be associated with nerve injuries, vascular injuries, trauma to the spinal cord, and epidural abscesses. Although rare, these adverse events are potentially catastrophic. Pharmacologic remedies for pain must also consider potential side effects that can occur even at therapeutic doses of over-the-counter remedies such as paracetamol (acetaminophen) or nonsteroidal anti-inflammatory drugs. Opioids are effective pain relievers but are associated with many side effects, some of which can be treatment limiting. A prevalent and distressing side effect of opioid therapy is constipation. Opioid-induced constipation is caused by binding to opioid receptors in the gastrointestinal system, making conventional laxatives ineffective. Peripherally acting mu-opioid receptor antagonists are a new drug class that offers the benefits of preserving opioid analgesia without side effects in the gastrointestinal system. An important safety concern, particularly among geriatric patients is the increasingly prevalent condition of polypharmacy. Many senior patients take five or more medications, including some that may be contraindicated in geriatric patients, duplicative of other drugs, have potential pharmacokinetic drug-drug interactions, or may not be the optimal choice for the patient's age and condition. Careful assessment of medications in the elderly, including possibly deprescribing with tapering of certain drugs, may be warranted but should be done systematically and under clinical supervision.</p

The ability of lumbar spine DXA and phalanx QUS to detect previous fractures in young thalassemic patients with hypogonadism, hypothyroidism, diabetes, and hepatitis-B: A 2-year subgroup analysis from the Taranto Area of Apulia Region.

BACKGROUND: Osteoporosis is a leading cause of morbidity in patients affected by β-thalassemia major or intermediate; we aimed to assess the association between demineralization observed in young thalassemic patients. METHODS: A total of 88 patients with β-thalassemia were recruited at Microcitemia Center of Taranto Hospital under the Prevention Osteoporosis and Fractures research project from 2008 to 2010. All the patients were screened with both dual energy x-ray absorptiometry (DXA) and quantitative ultrasound (QUS). T score and Z score values were obtained for each subject. RESULTS: The overall prevalence of demineralization was 84% with DXA and 70% with QUS, whereas normality was found in 16% of patients screened with DXA and in 30% of cases with QUS. Hypogonadism, hypothyroidism, diabetes mellitus, hepatitis-B, and the presence of previous fragility fractures were significantly associated with the demineralization status (lower T scores values) both with DXA and QUS. CONCLUSION: Our data confirm that DXA and QUS examinations are both useful for detecting bone demineralization in thalassemic patients

A Transcutaneous Fetal Visual Stimulator

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Markers of Bronchiolitis Obliterans Syndrome after Lung Transplant: Between Old Knowledge and Future Perspective

Bronchiolitis obliterans syndrome (BOS) is the most common form of CLAD and is characterized by airflow limitation and an obstructive spirometric pattern without high-resolution computed tomography (HRCT) evidence of parenchymal opacities. Computed tomography and microCT analysis show abundant small airway obstruction, starting from the fifth generation of airway branching and affecting up to 40–70% of airways. The pathogenesis of BOS remains unclear. It is a multifactorial syndrome that leads to pathological tissue changes and clinical manifestations. Because BOS is associated with the worst long-term survival in LTx patients, many studies are focused on the early identification of BOS. Markers may be useful for diagnosis and for understanding the molecular and immunological mechanisms involved in the onset of BOS. Diagnostic and predictive markers of BOS have also been investigated in various biological materials, such as blood, BAL, lung tissue and extracellular vesicles. The aim of this review was to evaluate the scientific literature on markers of BOS after lung transplant. We performed a systematic review to find all available data on potential prognostic and diagnostic markers of BOS